A researcher in molecular biology and a microbiologist, I have gradually specialised in the study of the interactions between pathogenic bacteria and their host cells, and in RNA-related mechanisms.

After a PhD thesis at the Pasteur Institute dedicated to the study of ribosome biogenesis, my post-doc project at the CNRS (Gif-sur-Yvette) aimed at the characterization of various aspects of nuclear RNA quality control mechanisms. We uncovered a new enzymatic activity in one of the best studied eucaryotic RNA degradation complexes, the exosome.

In 2008, I was recruited as a permanent INRAE researcher, where I am now a research director. From 2008 to 2014, working in Pasteur Institute, I investigated how the pathogenic bacterium Listeria monocytogenes subverts chromatin silencing in infected cells, thus modulating the type III interferon transcriptional response.

Since 2015, I have been heading at the Institute of Biology of École normale supérieure (IBENS) a research group exploring the fate of host RNA in response to infection. We are also gaining insight into the intracellular lives of Listeria and the dynamics of its secreted virulence factors in real-time microscopy.

I am regularly sharing my passion for research through broad audience initiatives, teaching, and via my Twitter account.