|
| Research |
Download PDF |
| Since 2015 |
Group leader at the Institute of Biology of École normale supérieure
(IBENS),
INRAE research director since 2022.
Research themes: Regulation of human cell gene expression in response to infection by intracellular bacteria;
dynamics of Listeria monocytogenes intracellular lifestyles and of the molecular dialogue
engaged with its host cell.
|
| 2008 - 2014 |
INRAE researcher at Pasteur Institute,
laboratory of Bacterial-Cell Interactions
(Pascale Cossart, group Hélène Bierne).
Research topic: Chromatin subversion and regulation of host gene expression by the pathogenic bacterium
Listeria monocytogenes.
|
| 2006 - 2008 |
Post-doc at the Center for Molecular Genetics (CGM) - CNRS,
Gif-sur-Yvette (France), team of Bertrand Séraphin.
Research topic: Nuclear RNA quality control mechanisms and exosome function in yeast and human.
|
| 2002 - 2006 |
PhD thesis at the Pasteur Institute, laboratory of Genetics of Macromolecular Interactions (Alain Jacquier), supervised by Micheline Fromont-Racine.
Research topic: Ribosome biogenesis in the yeast Saccharomyces cerevisiae.
|
| February - July 2000 |
Erasmus training at the Microbiology Institute of the Zürich
ETH (Pr. Thomas Leisinger’s laboratory) .
Research topic: Characterization of the γ-glutamyl-hydrolase IpuF, an enzyme involved in
the transformation of isopropylamine to L-alaninol by Pseudomonas sp.,
for biotechnological purpose.
|
| Summer 1999 |
Internship in La Pitié-Salpêtrière hospital, laboratory of
Mecanisms and Consequences of Neuronal Death,
supervised by Rita Raisman-Vozari.
Research topic: Histology of a murine model for Parkinson Disease.
|
|
| Education |
| 2002 - 2006 |
Habilitation to supervise research (HDR) in Microbiology-Virology (Paris 7 University).
|
| 2002 - 2006 |
PhD thesis in Microbiology-Virology from Paris 7 University at the Pasteur Institute.
|
| 1998 - 2002 |
Undergraduate studies at the École
normale supérieure de Cachan (now ENS Paris-Saclay),
Biochemistry and Bio-engineering department :
- DEA (Master’s degree) in Microbiology-Virology at Paris 7 University,
Cours Pasteur of Fundamental Microbiology,
- Agrégation (French degree for high-school teaching) in Biochemistry,
- Licence (Bachelor’s degree) and Maîtrise in Molecular and Cellular Biochemistry at Paris 7 University.
|
| 1996 - 1998 |
BCPST preparatory classes for competitive examinations in agronomy and life sciences.
|
|
| Supervision |
| Since 2015 |
Head of a research group at IBENS (4-9 members).
Supervision of three post-doctoral fellows, three PhD students, eighteen students (two rotation students, nine Master’s degree and seven undergraduates),
two engineers and a technician. Regular hosting of undergraduate students for theoretical or practical mini-projects. |
| 2003 - 2013 |
Co-supervision of a research engineer and a bio-informatician. Supervision of an assistant engineer and three Bachelor’s degree students for summer laboratory training periods. |
|
| Teaching |
| Since 2023 |
Professor in the biology department of École normale supérieure.
In charge of the M2 year of IMaLiS (Master’s degree).
|
| 2019-2022 |
Jury for the biology entrance exam of École normale supérieure.
|
| Since 2017 |
Yearly conference at ENS Paris-Saclay, cours
Great Discoveries in Life Sciences course (Bachelor’s degree).
|
| Since 2015 |
Co-organisation of the course Microbial Systems, IMaLiS, École Normale
Supérieure (Master’s degree).
|
| Since 2011 |
Yearly conference at ENS Paris-Saclay, Cell Biology of Host-Invasive Bacteria Interactions course (Master’s degree).
|
| 2014 - 2018 |
Organisation of a Molecular Cell Biology course for non-biologist scientific students at ENS
(Bachelor’s degree).
|
| 2017 - 2018
|
In charge of the Fundamental Biology for Health track, IMaLiS, École Normale
Supérieure (Master’s degree).
|
| 2005 - 2006 |
Lecturer at the Cours Pasteur of Fundamental Microbiology and Genome Analysis (Master’s degree).
|
| 2002 - 2005 |
Teaching assistant at Paris 7 University for Immunology exercise sessions and practical works (Bachelor’s degree).
|
|
A more detailed list of my teaching activities can be found here.
|
|
| Funding obtained |
| December 2013, 2 years |
Amorçage de jeune équipe, French Foundation for Medical Research (FRM). |
| June 2014, 3 years |
ATIP-Avenir Team (Inserm). |
| June 2014, 4 years |
Program Émergence(s) from Paris City, Medical Research and Health. |
January 2015, 2 years
& January 2017, 2 years |
MicroLife project from MemoLife Labex inter -institute and -thematic program (coordinator). |
| October 2020, 4 years |
LiVaLife, collaborative research project funded by the 2020 generic call launched by the French
l’National Research Agency (ANR) (coordinator). |
| Expertise |
Speaker at national and international scientific meetings.
A detailed list of talks I gave in congresses or seminars can be found here.
|
Ad hoc expert for grant proposals and peer-reviewer for scientific journals.
Jury member for thirteen PhD and a number of Master’s degree thesis defences. Member in nine PhD thesis committees.
|
| Since 2017 |
Member of the scientific council of the Microbiology department of INRAE.
|
| 2014-2018 |
Jury member for Complexité du Vivant doctoral school (Sorbonne University)
|
| 2013 - 2014 |
Member of the Pasteur Institute committee for ethics in animal experimentation.
|
|
| Around Science |
| Diffusion of Science |
Chronicles in biology in Le Monde (since 2018).
Member of the scientific committee of the Biennale du vivant hosted by ENS, the national museum of natural history, and the national school of decorative arts in partnership with Libération (2023).
Member of the scientific council for the exhibition DNA, the key of life by the association Science Ouverte (2022).
Escape
game in epidemiology
at the 28th Astronomy Festival in Fleurance (France).
Conferences for ENS open night (2016) and for high-school students (2014) on cell piracy by
Listeria monocytogenes.
Participation in a science/society
debate at Institut Henri Poincaré movie-club
Univers Convergents
after the screening of Jurassic Park.
Hosting of secondary school students for laboratory discovery weeks.
A more detailed list of my broad audience activitiess can be found here.
|
| Scientific events |
Co-organizer of three department and team retreats.
Co-organizer of scientific seminars and of the Pasteur Institute young researchers meeting (2004, 2005).
|
|
| Professional skills |
| Biology |
Advanced knowledge of usual concepts and techniques in molecular and cellular biology, RNA and protein
biochemistry, genetics of eukaryotes and prokaryotes, microbiology, host-pathogen interactions. Personal licence for experimentation on
mammalian organisms.
|
| Informatics |
Programming: LaTeX, HTML and PHP; practical use of biological analysis and office softwares under
MacOS and Windows systems, as well as of online databases. Member of IBENS web team.
|
| Languages |
Fluent English, conversation-level Spanish. |
|
| Member of learned societies and associations |
|
|
|
|
|